Buffalo Healthy Living News

Roswell Park Researchers Publish Findings on Agent Shown to Enhance Immunotherapy

2012-02-28T13:41:00.000-08:00

Conclusions from study of entinostat combination to be tested in kidney, prostate cancer clinical trials

BUFFALO, NY — Preclinical research by a team from Roswell Park Cancer Institute (RPCI) has demonstrated for the first time the way in which a class I histone deacetylase (HDAC) inhibitor, entinostat, appears to boost the effectiveness of cancer immunotherapy for treatment of some solid tumors. The findings support conclusions from earlier studies and also suggest that the approach merits further testing in clinical settings.

In a study involving models of renal and prostate cancer, recently published in the peer-reviewed scientific journal PLoS One, a team led by Roberto Pili, MD, Professor of Oncology, Chief of the Genitourinary Section and Co-leader of the Genitourinary Program, Department of Medicine, demonstrated the novel immunomodulatory effect through which entinostat, manufactured by Syndax Pharmaceuticals, Inc., appears to enhance the antitumor activity of Interleukin-2 (IL-2) for kidney cancer and of a survivin cancer vaccine (SurVaxM), developed at RPCI by Michael Ciesielski, PhD, and Robert Fenstermaker, MD, of the Department of Neurosurgery, for prostate cancer.

“Entinostat has an immunomodulatory effect on regulatory T cells, which are like brakes for the immune system and are present in many tumors,” Dr. Pili explains. “By suppressing these suppressor cells, entinostat releases the brakes and helps the immunotherapies to work better.”

The combination of a vaccine with approaches to deplete or suppress regulatory T cells, the researchers write, “represents a rational strategy in prostate cancer therapy” and one that “also has promising potential to be effective in other immunotherapies and in different tumors.”

Li Shen, PhD, a postdoctoral associate in the Department of Medicine, was lead author on the study. Drs. Ciesielski and Fenstermaker were also contributing authors, as were Swathi Ramakrishnan, Kiersten M. Miles, PhD, Leigh Ellis, PhD, and Paula Sotomayor, Department of Medicine; and Protul Shrikant, PhD, Department of Immunology.

The PLoS One article is titled “Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models,” and can be accessed online at:http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030815.

A clinical study testing the combination of entinostat with IL-2 in renal-cell cancer is underway at RPCI and other sites. For more information about that study, which is currently accruing participants, go to: http://www.roswellpark.org/clinical-trials/list/145208-0.

Additional clinical studies of the combination of entinostat and other immunotherapies are planned in prostate cancer and other solid tumors.

How Music Changes Our Brains

2012-02-28T11:54:00.003-08:00

Science is becoming increasingly interested in the relationship between sound and the brain. An expert explains
by Thomas Rogers, Salon.com

Music has never been more accessible. Just a decade ago, we were lugging around clunky portable CD players that weighed as much as a hardcover book and would skip whenever we made any sudden movement. Now our entire record collection (and thanks to new companies like Spotify, almost any other song on the planet) can fit into our phones. We can listen to music nonstop — on our commute, at work, at the gym and everywhere else we might want to. But what is this explosion of sound doing to our brains?

In their new book, “Healing at the Speed of Sound,” Don Campbell, an author who has written extensively about music and health, and Alex Doman, a specialist in technology in brain function, take an extensive survey about what the latest neuroscientific findings tell us about music and the brain. Although excessive noise has be harmful in a number of ways, music has been shown to improve children with learning disabilities, help elders feel more connected to the world, and even get people into better shape. It provides children with a “hook” for the brain’s memory centers, allowing them to retain more information, and it can play huge roles in modifying our moods.

Salon spoke to Campbell over the phone about the dangers of excessive noise, the importance of exercise music and why more children should learn how to play instruments.

As you write about in the book, there’s been a growing consensus in the last few years that sound can have some very strong effects on our overall health.

Science is beginning to ask very different questions than it was 20 or 30 years ago. Just 3 months ago, the World Health Organization published a 108-page study that absolutely shook me up. It argued that noise is the second greatest pollutant in the world today. Environmental noise affects cardiovascular disease, cognitive impairment in kids, sleep disturbance, tinnitus, not to mention just plain annoyance. If it’s too loud, whether it’s classical music, rock, whatever, it’s not good for us. And the numbers are just beyond me. The study said noise cost up 45,000 DALY [disability-adjusted-life years, meaning 45,000 years of "healthy" life worldwide are taken away by noise] per year.

I just returned from a week in New York City, and I have a little decibel app on my iPhone. On the subways it registered way over 100 decibels. When I was outside, I found myself covering my ears and needing to use my noise reduction headphones.

But as you point out in the book, the scientific community is increasingly interested in looking at the ways music can affect our brains.

Our home, our work, everywhere around us is overloaded with sound. By selecting certain kinds of music, we can improve our lives and decrease our stress. Music triggers responses: If I speak in rhythm and rhyme, for example, another part of your brain will be [activated than the one that simply responds to speech]. Music can relate to emotions. It creates autonomic automatic responses.

What was surprising to me was, as you point out in the book, fast-paced music actually has real effects on your ability to work out. In one 2009 study you cite in the book, college students biked faster or slower depending on what kind of music they were listening to — and it made it easier for them to push themselves.

If you put a rhythm behind your exercise, you don’t become as tired as quickly because of our natural tendency to fall into a pattern. If you want to do 100 pushups, you will start counting because you need that rhythmicity. The building of the railroads, for example, would never have happened as quickly without the use of repetitive work songs. One professor at the university of Northern Colorado has done extensive research into what they call rhythmicity and rehabilitation, showing that, for people who’ve had injuries, the use of rhythmic patterns, whether from a metronome or music sustains the ability to prolong exercise in rehabilitative therapy. It’s a technique called entrainment. The body creates the rhythm, and then the therapist uses the rhythm in a rehabilitative context.

From a neurological perspective, why is it important to listen to and play music from an early age?

The more participation there is with music early on — through singing and movement — the more it simultaneously activates multiple levels of the brain. If you look at the corpus callosum [of someone who plays music] there are more connections made between right and left sides. A child who is moving, dancing and singing learns coordination between their eye, ear and sound early on. And [the experience of participating in music education] helps integrate the social, the emotional and the real context of what we’re learning. There are studies that show children who play music have higher SAT scores, that learning to control rhythm and tempo not only help them get along with others but plants seeds for similar advantages when we get much older.

What about learning disabilities?

In many cases, a background rhythm will help and assist somebody with dyslexia or autism to speak and read in rhythm. Exposure to different kinds of patterns — high range, mid-range, low range, slow tempo, medium, high tempo — can help bring order to their thinking. In a 2001 study, one researcher found that brain activity changes when there is soothing music, and there is biological evidence that we can actually remove a great deal of the tension in frustrated children by exposing them to more soothing sounds. In the Journal of Complementary Medicine in 2007, there was a study that found that these children can channel more resources when they speak in rhythm and rhyme and when they play and listen to music.

What about the elderly?

Our hearing decreases radically after the age of 60, and often by the time we are in our 80s we don’t hear high frequencies and some sounds become more annoying and more confusing. Under different kinds of medication, tinnitus becomes more frequent. It’s a symptom, not a disease. By learning to tap a rhythm as one speaks with an elder, to use a drum, a simple hand drum, the size of a tambourine, to be able to translate and transfer the organization of speech and thought becomes much more effective. There’s a company called Oval Window that produces floors that vibrate, so elders they can literally hear better through the vibrations.

There are interesting studies on socialization. The more we lose our hearing, the more isolated we become. Music and rhythm help keep people wildly engaged in life. Gordon Shaw [a professor at University of California Irvine] has been a great leader in this field. My mother had dementia for 10 years, and once I spoke to her in rhythm or played songs on the piano that my dad used to play for her when they were young, it woke her up.

Our lives are also much more deeply enmeshed in music these days. Now that music players are so portable, it feels weird to leave the house without listening to something on my headphones.

If we live in a world where there is no silence or integration, we’re not as healthy as we could be. 125 years ago, all music was real and alive. We didn’t have radio and iPods, and now it’s just the opposite.

Right, and conversely we don’t have as much access to silence.

Silence is part of the brain’s pattern. It helps it reintegrate, like sleep, but we can’t shut our ears like we shut our eyes.

I also find that, now that listening to vast quantities of music is so easy, I get impatient 30 seconds into a song and skip forward to the next one for no real reason.

I love exploring iTunes, but you only get 20 seconds of something to see if you like it. It’s like an all-you-can-eat food bar, but you need to understand the nutrition of it. If you’re changing music every 30 seconds, then be sure to have 2 minutes of real silence in there. It goes back to chew your food so to speak before you swallow it.

In the book, you describe something called a “listening disability,” or “auditory processing disorder,” in which children process sound incorrectly. As you point out, 2 to 3 percent of children suffer from it, but it’s often misdiagnosed as ADHD or hyperactivity.

Listening disabilities were discovered by ear-nose-and-throat specialists early this century. They manifest themselves when students are not able to discriminate between sounds or they’re overwhelmed by sound. They may suddenly realize they misunderstand instructions, they have poor auditory memory, and are easily distracted, have reading difficulties and have language problems. Symptoms in auditory processing can affect our whole learning and communication system. The ear can cause difficulties within the other pairs of cranial nerves, like the vagus nerve that affects not only the diaphragm but also the heart and the larynx. If something is not right in our hearing, we may not be able to speak and talk about it in the correct way. I know of a doctoral student at the University of Edinburgh who is doing fine research looking at the auditory relationship on this point — we often don’t look at the ear as a source of reading and learning difficulties.

Clearly a lot of places are very noisy and there has been some argument that having a TV or radio on in the background when you’re trying to do work is very distracting to people. Does the science back that up?

Different ages need different sounds. The brains of high school and college students are still developing and myelinating in such a way that sometimes sound allows them to focus better. Some of the newer studies have found that if someone is just having music in the background studying, very structured music like Mozart and Vivaldi and Haydn is better than pop music or nonstructured music. But we’re all different. For someone who lives in a home where there is a television, a microwave, the heater, as well as traffic outside, their mind can do nothing but work at filtering out sounds. For that person, silence can be quite frightening. And that’s where music can be used as a bridge. I’ve worked in classrooms of third-graders that have very little attention span, but if you give them noise cancellation headphones, they can suddenly hear themselves think.

: Thomas Rogers is Salon's deputy arts editor. More Thomas Rogers

New Hope for MS Patients in Buffalo

2012-02-28T11:30:00.001-08:00

ByAnnette Pinder

Multiplesclerosis (MS) is an autoimmune disease in which the body’s immune systemattacks the central nervous system (brain and spinal cord). As a result, theprotective myelin coating (sheath) on nerve cells which functions much likeinsulation on an electrical wire, becomes damaged, and signals from the nervescan become slow or blocked. Characteristic lesions called “multiple scars” canbe seen on an MRI in a person with MS, which gives the disease its name.

Symptomsof MS can include weakness, numbness, tingling, balance and gait problems,problems with thinking, mood, and fatigue, bowel and bladder problems, sexualdysfunction, and problems with speech, swallowing or vision. MS patients oftenexhibit intolerance to heat making damaged nerves less efficient, bringing onsymptoms.

Thereare 400,000 MS patients in the US, and over 2.5 million worldwide. The diseaseis of particular concern in Western New York where the incidence issignificantly higher. This is because MS is correlated with colder climates andliving above 40 degrees from the equator. Higherincidences are also seen in Europe and in Caucasians of Scandinavian ancestry,although MS can affect any ethnic group.

MS isthought to occur as result of geography, environmental influences, and possiblygenetics. Currently researchersbelieve low vitamin D levels may affect MS. Symptoms usually occur between ages of 15 and 45 and two tothree times more likely in women. Interestingly, MS exacerbations and relapsesare less frequent during pregnancy, urging researchers to investigate the roleof female hormones on MS.

Sevendisease modifying medications (Avonex, Betaseron, Copaxone, Gilenya,Novantrone, Rebif, Tysabri) are currently approved for the treatment ofRelapsing Remitting Multiple Sclerosis (RRMS). In September 2010, fingolimod(Gilenya) became thefirst oral medication to enter the market. According to Malti J. Patel, M.D. who has conducted severalMS clinical trials at the Dent, “This is a very exciting time for MS, and moredrugs are expected to enter the market in the coming years, giving patients andphysicians options to tailor MS therapy to specific patients.”

But Dr.Patel urges patients to “stick with what works for you and work with yourneurologist to choose the most effective medication for you, and one that youare willing to take regularly.” She says, “All MS drugs are effective, and haveadvantages and disadvantages. Currently approved treatments can slow disease progress and provideimproved quality of life, allowing patients to live more normal lives for alonger period of time.”

Dr. Patel isMedical Director for the Multiple Sclerosis Clinic at DENT Neurologic Institute(DENT). She is an Attending Neurologist at DENT and a consulting attending for the Primary Brain Tumor andNeurology Clinic at Roswell Park Cancer Institute. To make an appointment tosee Dr. Patel call 716-250-2000.

DENT is conducting a researchstudy for patients between the ages of 18 and 55 being treated for a relapsingform of MS, who have had symptoms return twice during the past two years oronce within the past year. Qualified participants will receive study-related exams and either aninvestigational drug, or an approved medication called Rebif. To find out more contact MichelleRainka,PharmD at 716-250-2038 or Kristin Surdam at 716-819-4117.

Can Dandelion Tea Cure Cancer?

2012-02-28T08:43:00.001-08:00

Dandelion tea touted as possible cancer killer

Trials planned at Windsor Regional Cancer Centre in Ontario

CBC News

Posted: Feb 16, 2012 1:08 PM ET

Last Updated: Feb 16, 2012 2:16 PM ET

Read 66comments66

Researchers hope to test dandelion tea on patients at a Windsor, Ont., cancer clinic after it was found the roots killed cancer cells in the lab. (Pat Jeflyn/CBC)

Researchers hope to test dandelion tea on patients at a Windsor, Ont., clinic after it was found the roots of the weed killed cancer cells in the laboratory.

The promising research is being led by a University of Windsor oncologist, in association with the Windsor Regional Cancer Centre.

Dr. Caroline Hamm said dandelion root extract is unique, and is one of the only things found to help with chronic myelomonocytic leukemia.

"It was really unusual to find a product that had efficacy in that area," said Hamm.

Some patients swear by it

John DiCarlo, 72, was admitted to hospital three years ago with leukemia. Even after aggressive treatment, he was sent home to put his affairs in order with his wife and four children.

The cancer clinic suggested he try the tea. Four months later, he returned to the clinic in remission. He has been cancer free for three years.

He said his doctor credits the dandelions.

"He said, 'You are doing pretty good, you aren't a sick man anymore'," DiCarlo told CBC News.

Talk to your doctor

The roots of the common dandelion were ground up and made into tea. According to researchers, early results show that the tea kills cancer cells in the lab.

Using dandelion tea extract to treat leukemia is not a new idea. The Memorial Sloan-Kettering Cancer Center in the U.S., among other research sites, has been looking at the plant since at least 2010.John DiCarlo, 72, says dandelion tea saved his life, after other medical treatments for his leukemia failed. (Steven Bull/CBC)

Hamm said the tea doesn't work for everyone and they need to find out why. The first phase of the trials will attempt to determine the right dose to administer.

Hamm was convinced that the weed contains an active ingredient, but warned "it can harm as well as benefit." She said taking dandelion extract tea could interfere with regular chemotherapy, and she urged patients not to mix the natural remedy with other cancer drugs without speaking to a doctor first.

The researchers have filed an application with Health Canada. If it's approved, Hamm expected to start the first phase of the trials in about two to three months.

Phase 1 involves 21 cancer patients where the standard of care is not working. Hamm said it would include patients with a wide variety of cancer types. The first phase should last six to eight months, she said.

Phase 2 will look at which types of cancer dandelion extract works best on, based on the results of Phase 1.

Daemen College Physical Therapy Wound Clinic

2012-02-28T08:03:00.000-08:00

Daemen College plans to establish a physical therapy wound clinic in Cheektowaga to treat those who suffer from chronic wounds, the college announced this week.

The clinic is set to be located at the Center for Skin Integrity on Union Road in Cheektowaga. It was not immediately known when the college plans to open the facility.

The John R. Oishei Foundation awarded $530,000 to Daemen to support the clinic, plus establish a wound care academy to train Western New York practitioners in chronic would healing care, the college said. The academy will ultimately provide clinical education for up to 120 physical therapy students in the region per year and also seek to create a state registered certificate in wound care for licensed health care professionals.

Chronic wounds are wounds that do not heal. They include infections, pressure and diabetic ulcers, burns, radiation, frostbite, refractory cysts and venous and arterial ulcers.

Researchers at Daemen College, along with the University at Buffalo and Roswell Park Cancer Institute, have studied chronic wounds for years. The three entities, led by Daemen, are investigating ways to predict healing outcomes for chronic wounds that prevent full recovery.

Officials expect the new clinic to provide research opportunities for faculty, students and practitioners related to treatment of chronic wounds at several levels. In recent years, the Daemen College Center for Wound Healing Research has secured more than $3.8 million in funding from industry, private foundations and the federal government to support research.

RIA Reaching Others With Energy Drink Research

2012-02-28T07:48:00.000-08:00

Expert Advice from RIA Researchers

ATHLETES: Energy drinks before or during games or practices? Probably not
a good idea. Though often confused, energy drinks are not sports drinks. Where Gatorade or Powerade are designed to provide hydration and replace electrolytes, caffeine actually contributes to dehydration. Adults and especially children may experience headaches, heart palpitations, hypertension, or blackouts
if they combine energy drinks with heavy exercise.

CAFFEINATED COCKTAILS: Combining alcohol (a depressant) with caffeine
(a stimulant) may make drinkers look, sound, and feel less drunk than they actually are. Underestimating one’s own intoxication puts you at greater risk for drunk driving, alcohol poisoning, and even sexual victimization. Mixing caffeine and alcohol may also lead to heavier drinking than alcohol alone for three reasons:

(1) caffeine postpones the sleepiness associated with intoxication, so you can drink longer; (2) energy drink flavors mask the taste of alcohol, so drinks taste better; and (3) caffeine has a “priming” effect on alcohol—that is, it strengthens cravings for another drink.

CAFFEINE: Many consumers of energy drinks and other caffeinated beverages forget that caffeine is a psychoactive stimulant drug, and like other drugs, it is highly addictive. Just like alcohol, if you’re going to drink energy drinks, do it responsibly! Unlike soft drinks, there are no official limits on how much caffeine an energy drink may contain. Read the label, and if it doesn’t specify the exact caffeine content (many don’t), go on-line and find out. Knowledge is power.

MYSTERY INGREDIENTS: Energy drinks typically contain a brand-specific proprietary blend of plant and herbal extracts. Most of these ingredients (such as gingko biloba or ginseng) are probably harmless. Others may not be.Energy drinks are highly caffeinated beverages designed to provide a short- term energy boost.These drinks typically contain as much caffeine as a cup of coffee and three times as much as a standard soft drink, with some brands containing much higher doses. Energy drinks also contain sweeteners, amino acids such as taurine or l-carnitine, massive doses of B vitamins, and plant or herbal extracts such as gingko biloba, ginseng, or milk thistle. The potential interactions among these ingredients are not well understood.

With sales expected to approach $20 billion a year by 2013 in the U.S. alone, energy drinks such as Red Bull, Monster, and Rockstar have become staples of the adolescent and young adult market. Although provocatively named brands such as Full Throttle, Daredevil, Havoc, Rage, Bawls, Who’s Your Daddy, Whoop Ass, and Extreme Ripped Force are designed to appeal to a target demographic of 18-25 year olds, they are nearly as common among high school students.

Excessive energy drink use is associated with several potential health risks. Overuse can lead to symptoms ranging from mild (headaches, jitteriness, anxiety) to severe (insomnia, heart palpitations, seizures). Poison control centers and emergency rooms have documented a rapidly growing number of cases of caffeine intoxication involving energy drink use, particularly when coupled with alcohol or other substance use. After several highly publicized cases in 2010, the FDA no longer permits ready-to-drink alcoholic beverages such as Four Loko, Joose, or Maxx to contain caffeine. However, caffeinated mixed drinks such as Red Bull, vodka or Jagerbombs remain extremely popular.

Timely Research

Highlights of RIA research findings in this area included:

Risk-taking and energy drink use in college students. Undergraduate students who used energy drinks frequently were three times as likely to smoke cigarettes, abuse prescription drugs, or be in a serious physical fight as infrequent users or nonusers. Frequent energy drink consumers also reported drinking alcohol, having alcohol-related problems, and using marijuana about twice as often as less frequent consumers. Other risk behaviors associated with frequent energy drink use included unsafe sex, not using a seatbelt, participating in extreme sports, and doing something dangerous on a dare.
Demographic differences. Men were significantly more likely to consume energy drinks than women (46% vs. 31%). Whites were also significantly more likely to consume them than African Americans (40% vs. 25%).

Energy drinks and alcohol. Two thirds of college student energy drink users also used energy drinks as mixers with alcoholic beverages.

Substance use and energy drink use in musicians. In a RIA study of amateur and professional musicians between the ages of 18 and 45, energy drink users were more likely than nonusers to report misuse of legal substances, including binge drinking (76% vs. 59%), alcohol-related problems (78% vs. 69%), and misuse of prescription drugs (31% vs. 13%). Energy drink users were also significantly younger on average (25.7 years vs. 30.4 years) and scored higher on personality measures of sensation-seeking, an attraction to novel and varied experiences.

For example, the bitter orange found in some brands is closely related to ephedra, a compound banned by the FDA in 2004 due to a number of consumer deaths. Because energy drinks are classified as dietary supplements, their content is not subject to direct regulation or oversight by the FDA. It’s up to the user to investigate the label. Buyer beware-- Know what you’re drinking!

PARENT ALERT: Because they are smaller and their brains are less developed, children are even more sensitive to the health effects of caffeine use than adults are. Kids are at greater risk for caffeine intoxication and their consumption habits should be subject to adult supervision. There is also evidence to suggest that heavy energy drink users are at higher risk for other problem behaviors, such as smoking, drug use, binge drinking, unsafe sex, or fighting. Energy drink use is less of a “gateway drug” than a potential red-flag warning sign for other health-compromising activities.

Excessive energy drink use is associated with several potential health risks. Overuse can lead to symptoms ranging from mild (headaches, jitteriness, anxiety) to severe (insomnia, heart palpitations, seizures). Poison control centers and emergency rooms have documented a rapidly growing number of cases of caffeine intoxication involving energy drink use, particularly when coupled with alcohol or other substance use. After several highly publicized cases in 2010, the FDA no longer permits ready-to-drink alcoholic beverages such as Four Loko, Joose, or Maxx to contain caffeine. However, caffeinated mixed drinks such as Red Bull & vodka or Jagerbombs remain extremely popular.

RIA Reaching Others with Research on Drinking and Drugs in the Workplace/Workforce

2012-02-27T08:44:00.001-08:00

A seminal study at UB’s Research Institute on Addictions (RIA) reported that during the course of the year “15% of the U.S. workforce has used or been under the influence of alcohol at work.” This prevalence study of workforce-workplace substance use included data obtained from interviews with 2,800 employed adults, ages 18-65, who resided in the contiguous U.S. and District of Columbia between 2002-03.

Substance use in the workplace occurs:

Just before coming to work
On lunch hours and other breaks
Due to intoxication at work or hangover from the night before

Since that study, additional important research results about substance use on the job have been released by RIA.

Timely Research

Highlights of research findings in this area included:

8.9 million workers drank alcohol at least once during the workday. Most workers who drink during the workday do so during lunch breaks, though some drink while working or during other breaks.
2.3 million workers have consumed alcohol at least once before going into work.
Approximately 63% of the workforce reported that they could easily bring alcohol into work, use alcohol while working, use alcohol during lunch and other breaks, or obtain alcohol at work. Similarly, 59% of the workforce reported that they could easily engage in the same behaviors regarding illicit drugs.
Men’s alcohol use and impairment at work was more prevalent than women’s. Younger employees worked under the influence of alcohol or with a hangover more than older workers, and unmarried workers more than married workers.

Occupations showing the highest rates of workplace alcohol use and impairment were: management, sales, arts/entertainment/sports/ media, food preparation and serving, building and grounds maintenance.

Illicit drug use in the workforce involved an estimated 14% or 17.7 million workers; illicit drug use in the workplace involved an estimated 3% or 3.9 million employed adults.

A permissive workplace substance use climate impacts perceptions of workplace safety, work strain, and employee morale among employees who do not use substances at work.

What it Means to Main St.

Since 1994, multi-year awards funding this area of research have added to the local economy by the creation of jobs, paychecks spent in housing, retail, school and entertainment, as well as in the growth of suburban and rural communities in the region. RIA’s 160 staff members reside in and contribute to 18 different local municipalities as taxpayers, consumers, parents, students, volunteers and much, much more. Three prominent NIH-funded studies in this research area include:

1994 - 2000 $560,000

Work, Alcohol and School Performance Among Adolescents

2000 - 2004 $1.4 million

Workplace Substance Use: A National Prevalence Study

2007 - 2012 $2.2 million

Work Stress And Alcohol Use:
A National Study of Unresolved & Unexplored Issues

13% reported exposure to a co-worker who used or was impaired by an illicit drug during the workday; 23% of the workforce reported exposure to a co-worker who used or was impaired by alcohol during the workday. Exposure to a permissive workplace substance use climate differed by gender, age, occupation and work shift.
Illicit drug use is not distributed equally across employers. Among young

men in high-risk occupations, 56% report overall illicit drug use and 28%
report workplace illicit drug use. Likewise, among young women in high-
risk occupations, 43% report overall illicit drug use and 11% report workplace illicit drug use.

Oishei Foundation Awards $60,000 to Crisis Services’ “AfterHours” Program

2012-02-27T08:03:00.004-08:00

(BUFFALO) February 16, 2012 — The John R. Oishei Foundation has awarded Crisis Services a grant of $60,000 to help to support the clinical AfterHours Program in 2012.

A New York State mandate in 2011 required that all mental health clinics have a licensed mental health professional available on-call 24 hours a day, seven days a week. In response, Crisis Services created the AfterHours program and, with the seed support of the Oishei Foundation, 11 agencies (including 39 clinics in four counties) contracted with Crisis Services to provide coverage during a nine month demonstration project. The results of the demonstration project were excellent, resulting in more than 8,000 calls and diverting many clients from unnecessary emergency room visits.

The new grant by the Oishei Foundation recognizes the success the program has realized and will help defray the costs of continuing this project in 2012.

The Oishei Foundation appreciates the importance of organizations that provide invaluable “safety-net” services for our community and recognizes the critical role Crisis Services plays.

The John R. Oishei Foundation strives to be a catalyst for change to enhance economic vitality and the quality of life for the Buffalo Niagara region. The Foundation was established in 1940 by John R. Oishei, founder of Trico Products Corporation.

gray got you blue?

2012-02-23T13:25:00.005-08:00

by Dr. Kathleen Moore

Do you find yourself feeling more tired, sluggish, and irritable as the days grow shorter? Are you sleeping more, eating more, craving sweets and other carbohydrates, perhaps gaining weight? Is it harder to get out of bed each morning?

If you find that these symptoms occur regularly each winter, starting sometime between September and November, and then completely disappear once spring arrives, you may have Seasonal Affective Disorder, or SAD. SAD can vary in intensity: for some it is relatively mild, known as “winter blues;” for others it can be seriously disabling. It occurs much more frequently in women than in men, typically begins between age 18 and 30, and is more common in regions farther from the equator. SAD is a very real disorder, and can even be life-threatening if someone becomes suicidal.

Experts believe that SAD is caused by increased production of the hormone melatonin. Melatonin, produced by a small gland in the brain called the pineal gland, is related to sleep and circadian rhythms, but may also cause symptoms of depression. It is produced at increased levels in the dark; therefore, when days become shorter and darker, production of melatonin increases.

Bright light signals the brain to block secretion of melatonin. Bright light therapy as a treatment for SAD was first pioneered by psychiatrist Dr. Norman Rosenthal in 1984. Treatment involves sitting in front of a very bright, preferably full-spectrum, light source from 30 minutes to several hours each day, generally in the early morning hours. Often people will eat breakfast or read the morning paper while using the light. The key to its effectiveness seems to be regularity of use, but long-term compliance with treatment is often difficult to maintain.

The SSRI antidepressants such as Paxil, Zoloft, and others, have also been effective in treating SAD – and some people find taking a pill much easier and less time-consuming than sitting in front of a light box every day. Counseling and psychotherapy can also help individuals with SAD to manage and cope with their symptoms.

Other tips for battling the winter blues include:

• Exercise on a regular basis either out doors or indoors near a window or bright light source.
• Install brighter bulbs in your work and living spaces.
• Maintain a regular daily pattern of going to sleep and awakening.
• Put your bedroom lights on a timer to switch on half an hour before awakening,
or invest in a “dawn simulator,” which gradually increases the intensity of light.
• Sit next to windows in classrooms and restaurants.
• Arrange social activities outdoors. Out door light, even when the sky is overcast,
provides as much or more light than a light box.
• If possible, arrange a winter vacation to a warm and sunny climate.

As Dr. Rosenthal points out, winter doesn’t have to be a bleak and dismal season. Exercising, eating a balanced diet, and trying to maximize your exposure to what natural light there is during the winter months can help most people. For others, don’t be afraid to consult a professional. Light therapy, combined with counseling and antidepressant treatment where indicated, can make a world of difference in staying sunny throughout the Rochester winter.

NOTE: Tanning beds are NOT an effective treatment for SAD, because their light sources are high in ultraviolet rays, which can damage your eyes as well as your skin.

ABOUT THE AUTHOR: Kathleen Moore has a Ph.D. in Counseling Psychology, and currently works as an administrator at the University of Rochester. Contact her at kmoore@rochesterhealthyliving.com.

Warsaw VA Health Care Transitions to Batavia

2012-02-23T12:38:00.001-08:00

VA Western New York Healthcare System announced Warsaw VA Community Based Outpatient Clinic
located at Wyoming County Community Hospital, 400 North Main Street will shift Veterans’ care to Batavia VA medical center, 222 Richmond Avenue beginning March 3, 2012. The realignment will allow for improved access; five days per week primary care from the current two days per week at Warsaw and availability of many specialty services in one location. In addition, there will be no loss of jobs and Veterans will be seen by the same primary care providers they currently see at the Warsaw site.

“We are confident this transition will provide improved access to appointments and all specialty care for Veterans in the Warsaw and surrounding area,” stated Miguel Rainstein, M.D, Chief of Staff, VA Western New York Healthcare System.

A market study has shown a large majority of the 798 Veterans who use the Warsaw VA Clinic already
elected to receive care from one of five VA sites in the past year in addition to the Warsaw VA clinic with the most often utilized site being Batavia. Appointments at the Batavia site can be made by calling 585-297-1050. To assist with the transition, letters are being sent to all patients that use the Warsaw VA clinic and a free Veterans Transportation System between Warsaw and Batavia VA is in place and will operate five days per week with four pick up points within Warsaw including the current location of the Warsaw clinic. To reserve a spot, call 716-862-6800 as soon as medical appointment is made.

Nasty "Superbug" is Being Studied by UB Researchers

2012-02-22T12:19:00.000-08:00

It's virulent, potentially drug-resistant, strikes otherwise healthy, young patients, and Buffalo has already seen one case

UB's Russo has been awarded an NIH award aimed at discovering new therapeutic or vaccine targets to better treat or prevent this under-recognized infection.

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Contact

Ellen Goldbaum

goldbaum@buffalo.edu

716-645-4605
twitter @egoldbaum

Release Date: February 17, 2012

BUFFALO, N.Y. -- University at Buffalo researchers are expressing concern about a new, under-recognized, much more potent variant of a common bacterium that has surfaced in the U.S.

"Historically, in Western countries, classical strains of Klebsiella pneumoniae have caused infections mostly in sick, hospitalized patients whose host defense systems are compromised," says Thomas Russo, MD, professor in the Department of Medicine at the UB School of Medicine and Biomedical Sciences and head of its Infectious Disease Division.

"But in the last 10 to 15 years, a new variant of it has begun causing community-acquired infection in young, healthy individuals," he says. "This variant causes serious, life-threatening, invasive infections and is able to spread to other organs from the initial site of infection."

Perhaps most important, says Russo, these hypervirulent strains of Klebsiella pneumoniae have the potential to become highly resistant to antibiotics, similar to Escherichia coli and classical Klebsiella pneumoniae.

"These hypervirulent strains are the next 'superbugs' Â–in-waiting," he says. "If they become resistant to antibiotics, they will become difficult, if not impossible to treat."

With recent funding from the National Institutes of Health under a program to fund high-risk, high-reward research, Russo and his UB colleagues are studying the microbiology of the new variant of Klebsiella pneumoniae in an effort to identify the genes that make it hypervirulent so they can figure out how to stop it in its tracks.

"Infections due to highly resistant bacteria are becoming increasingly problematic," says Russo. "We are continually threatened by a 'post-antibiotic' era. The combination of a bacterium that is both highly virulent and resistant to antimicrobials is double-trouble."

The researchers' concern stems from the fact that classicalKlebsiella pneumoniae is one of the bacterial species that can easily acquire mobile genetic units, called plasmids, that contain multiple genes that confer high levels of antimicrobial resistance.

"That's in part why we're concerned," says Russo. "We know that this bacterium has the potential to acquire these plasmids and it almost certainly will."

He notes that most bacteria that have proven to be resistant to most or all of the drugs currently available do not usually infect healthy members of the community.

"What is alarming about the hypervirulent Klebsiella pneumoniae is that they do possess the potential to infect healthy people," says Russo. "If this hypervirulent bacterium also becomes highly resistant to antimicrobials, we will have a significant problem to manage. We hope that our research and that of others can prevent this possibility."

While the new hypervirulent variant was first seen exclusively in in the Pacific Rim, it has now been found in several cities in North America, including Buffalo, and in Europe, Canada, Israel and South Africa as well. The UB researchers characterize it as "under-recognized" both by physicians and microbiology laboratories.

The disease most commonly presents as a liver abscess, which is not typical for otherwise healthy patients.

"This new variant presents with unique and scary features: first is its tendency to infect young, healthy people in the community and the second is its unique propensity for metastatic spread to other parts of the body," says Russo. "It spreads to sites beyond the initial source of the infection, such as the lungs, the central nervous system and the eye, potentially causing loss of vision. If infection spreads to the brain, there can be brain damage as well. Between 10 and 30 percent of cases are fatal."

In Buffalo, this hypervirulent variant of Klebsiella pneumoniae was identified in an otherwise healthy, young person several years ago. The patient, who was in his 20s, was hospitalized for several months before making a full recovery. Similar cases are causing concern throughout the international infectious disease community.

At the moment, most cases of hypervirulent Klebsiella pneumoniae resolve if treated aggressively with antibiotics and drainage of abscesses; however, some infections, despite optimal treatment, result in a persistent morbidity or death, Russo says.

He notes that the potential for the bug to acquire drug resistance is adding a sense of urgency to the research.

Russo says that microbiology labs should be aware that an important characteristic of these hypervirulent strains (also known as hypermucoviscous strains) is that when bacterial colonies grown on a solid surface in the laboratory are stretched by a common microbiology tool, called an inoculation loop, they form a viscous "string" greater than 5 millimeters in length.

Russo's team at UB is now beginning to develop a clearer picture of this formidable bacterial opponent.

In November, he and his colleagues published a PLoS ONE paper that showed that hypervirulent Klebsiella pneumoniaeacquires iron more efficiently than the usual strains of K. pneumoniae.

"With the NIH grant, we hope to further elucidate the precise details of the bacterial factors that are responsible for hypervirulent Klebsiella pneumoniae acquiring iron so much more efficiently," he says. "The goal of this line of research is that these iron-acquisition factors possessed by hypervirulent Klebsiella pneumoniae will then lend themselves as therapeutic or vaccine targets so that we can better treat or prevent infection."

In addition to Russo, other UB researchers working on hypervirulent Klebsiella pneumoniae are Alyssa S. Shon, an Infectious Diseases Fellow in the Department of Medicine; Janet Beanan, Ulrike MacDonald, Daniel Metzger and Ruth Olson, all research technicians in the Department of Medicine, and Alex Pomakov, a UB undergraduate majoring in biomedical sciences. Mark P. Visitacion, MD, a former Infectious Diseases Fellow in the UB Department of Medicine, was also part of the team.

ACSM, AFAA Grant CEU Approval to BWI’s Health Education Certificate Programs

2012-02-22T12:06:00.000-08:00

BUFFALO, N.Y., February 18, 2012 – Fitness industry professionals have three new courses to consider when fulfilling their professional development responsibilities. BWI National Health Promotion Training Institute’s health education certification courses have been approved for continuing education units (CEUs) by two additional national fitness industry associations.

BWI has been named a continuing education provider by the American College of Sports Medicine (ACSM) and Aerobics and Fitness Association of America (AFAA). ACSM is the largest sports medicine and exercise science organization in the world, promoting and integrating scientific research, education and practical applications of sports medicine and exercise science to maintain and enhance physical performance, fitness, health and quality of life. AFAA is the world's largest fitness educator, delivering comprehensive cognitive and practical education for fitness professionals.

BWI’s three courses, which may be delivered through a web-based learning platform or via onsite education in the traditional classroom setting, include:

· BWI Health Promotion Coordinator Certification: four-hour course provides a foundation for successfully implementing and managing an employee wellness program; ideal for human resource professionals and wellness managers/team members

· BWI Personal Health Certification: 12 interactive, 30-minute modules address lifestyle and behavior changes necessary to leading a healthier life; ideal for human resource professionals and wellness managers/team members for professional growth, as well as for integrating with employee incentive-based wellness programs

· BWI "Be Fit Kids" Instructor Certification: four-hour course trains facilitators to lead, implement and instruct students from kindergarten through sixth grade in an outcome-based, results-oriented behavior modification program that empowers children and families to take responsibility for their health; ideal for educators and recreation staff members

“We are excited that ACSM and AFAA – two highly regarded national exercise and fitness associations – see the value in our certificate programs,” said Shawna Dosser, BWI president and CEO. “Our online courses, which are conveniently accessible to professionals anywhere at any time, are delivered through an online learning management system and include pre- and post-tests to measure knowledge improvement.”

The Human Resource Certification Institute (HRCI) has also approved BWI for CEUs, and through BWI’s affiliate Learning Partners, CEUS are available from the International Association for Continuing Education and Training (IACET), Board of Certification (BOC), NYS-PT Board and the National Board for the Certification of OTs. Pending approval are CEUs from the National Exercise Trainers Association (NETA) and National Academy of Sports Medicine (NASM).

The BWI National Health Promotion Training Institute is a subsidiary of BWI Health Promotions, which provides comprehensive wellness management services and health education training programs for corporations, schools and communities. The BWI National Health Promotion Training Institute was developed to offer web-based certificate programs for individuals and/or professionals looking to enhance their personal knowledge in the field of health promotion. As a New York state regional health promotion leader, BWI’s presence is expanding into the national business market with program delivery throughout the United States.

To learn more about BWI’s courses, contact Dosser at traininginstitute@bwihp.com or by calling 1-800-606-7422 or 716-992-2732. Visit www.bwihp.com for course details and to register online at the BWI e-store.

Rochester Immediate Care Receives Joint Commission Accreditation

2012-02-22T11:27:00.000-08:00

February 20, 2012 - Rochester Immediate Care facilities in Greece and Webster join the highly select ranks of urgent care centers nationwide to display the Joint Commission Gold Seal of ApprovalTM

When patients, insurers, policy makers, regulators and medical professionals seek a comprehensive measure of a healthcare provider’s quality of care and safety for patients, there is one “gold standard” they rely on: accreditation from The Joint Commission.

The two freestanding Rochester Immediate Care facilities in Greece (2745 West Ridge Road) and in Webster (1065 Ridge Road) join the highly select ranks of urgent care centers nationwide to receive accreditation from The Joint Commission and eligible to display its Gold Seal of ApprovalTM. The Rochester Immediate Care facilities are led by Janet Williams, MD, FACEP in Greece and Pam Sullivan, MD, FACP in Webster.

Formerly known as the Joint Commission on Accreditation of Healthcare Organizations, The Joint Commission is regarded as the nation’s preeminent independent body for auditing and measuring quality in healthcare; its designation of accreditation is highly valued by hospitals, laboratories and clinics nationwide, including Rochester-area hospitals such as Strong Memorial, Highland, Rochester General and Unity.

Unlike certification, which simply defines the characteristics of an urgent care center based on a completed application form, Joint Commission accreditation recognizes quality of care and safety based on Joint Commission officers’ personal examination of a facility’s records, policies and procedures and unannounced site visits for detailed inspections.

Of the more than 8,700 urgent care centers in the United States, only a select few are currently accredited by The Joint Commission. The Urgent Care Association of America worked collaboratively with The Joint Commission in 2008 to establish this accreditation, which both entities recognize.

In addition, insurers and policymakers recognize Joint Commission accreditation when making decisions on licensing, certification and contracting. For example, many states waive routine on-site surveys of a facility if it maintains its Joint Commission accreditation. The Centers for Medicare and Medicaid Services recognizes Joint Commission accreditation as a factor for participation in CMS reimbursement programs.

Accreditation is totally voluntary and facilities pay a fee to cover the expenses of the surveys and on-site visits from The Joint Commission.

“Organizations that strive for accreditation in ambulatory care from The Joint Commission are demonstrating the highest commitment to quality and safety to their patients, staff and their community,” says Michael Kulczycki, executive director, Ambulatory Care Accreditation Program, The Joint Commission. “I commend Rochester Immediate Care for successfully achieving this pinnacle and for its dedication to continually improving patient care.”

Rochester Immediate Care is managed by The Exigence Group of Amherst, New York, which also manages urgent care facilities in Buffalo and in Austin, Texas. The entire system of urgent care facilities received Joint Commission accreditation.

“With this Joint Commission Gold Seal of ApprovalTM, we join an elite group of urgent care providers whose ability to deliver the highest level of patient care is formally recognized,” said Gregory F. Daniel, MD, MBA, Chief Executive Officer, The Exigence Group. “We urge everyone—patients, insurers, regulators, policy makers and physicians—to consider this accreditation, and our commitment to the high quality of care it acknowledges, when making personal, patient-centered and policy decisions.”

Achieving Accreditation

Inspectors from the Joint Commission conducted both announced and unannounced visits to Rochester Immediate Care’s two facilities as well as to the Exigence corporate headquarters in Buffalo. The visits were made in November and December of 2011. Among the checklist of items they scrutinized and evaluated are:

· Environment of Care: Physical plant requirements, patient and employee safety, and cleanliness

· Emergency Management: Including mitigation efforts, assessment of preparedness, review of response to emergency and recovery after event

· Human Resources, Credentialing, Privileging: Consistency in the hiring and termination process, assuring that all providers are competent to perform their duties, review of corporate based training and orientation efforts, Quality Assurance plans, continuing education and ongoing training

· Infection Prevention and Control: Activities, education, training, and planning for risks of infections

· Leadership: Ensuring the organization holds to its published Mission, Vision and Values

· Medication Management: Pharmacy services planning, administration, monitoring and evaluation

· National Patient Safety Goals: Incorporation of NPSG into the regular practice

· Provision of Care: AIDET, assessment of patient, delivery of care, coordination of care and future treatment needs

· Record of Care: Private health information management, discharge summaries, imaging reports, etc.

· Waived Testing: Lab Controls, policies and procedures, training and education

Maintaining Accreditation

Accreditation from The Joint Commission is not permanent. To maintain accreditation, an ambulatory care organization must undergo an on-site survey by a Joint Commission survey team every three years. The objective of the survey is not only to evaluate the organization, but to provide education and guidance that will help staff continue to improve the organization’s performance. Surveys are conducted by professionals with at least five years of leadership experience in an ambulatory care organization, and a strong educational background. Ambulatory care surveyors have advanced medical or clinical degrees and receive continuing education to keep them up-to-date on advances in quality-related performance evaluation.

The survey process focuses on evaluating actual care processes by tracing patients through the care, treatment and services they received. In addition to these patient “tracers,” surveyors conduct systems tracers to analyze key operational systems that directly impact the quality and safety of patient care. Surveyors use pre-survey information, from the Priority Focus Process, to conduct a more organization-specific and consistent survey.

About The Exigence Group

Headquartered in Amherst, New York, Exigence is a national healthcare management organization owned and managed by physicians. With clients throughout the United States, Exigence develops and manages Emergency Medicine, Hospitalist, Urgent Care, Occupational Medicine and Patient-Centered Medical Home programs. The Exigence Group manages over 600,000 patient visits annually, including 118,000 urgent care visits in 2011. In addition, Exigence provides consulting services in areas such as emergency department design, information technology infrastructure, electronic medical record systems, on-call panels and more. Learn more about The Exigence Group at www.theexigencegroup.com.

About The Joint Commission

Founded in 1951, The Joint Commission seeks to continuously improve healthcare for the public, in collaboration with other stakeholders, by evaluating health care organizations and inspiring them to excel in providing safe and effective care of the highest quality and value. The Joint Commission evaluates and accredits more than 18,000 healthcare organizations and programs in the United States. The Joint Commission also provides certification of more than 1,700 disease-specific care programs, primary stroke centers, and healthcare staffing services. An independent, not-for-profit organization, The Joint Commission is the nation's oldest and largest standards-setting and accrediting body in health care. Learn more about The Joint Commission at www.jointcommission.org.

For Further Information: Bob Loeb, 585.586.8840 or 585.261.8840 (cell) Claire Jones, 716.817.2928, 716.480.2529 (cell)

Mercy Hospital rolls out new cardiac procedure

2012-02-22T11:02:00.000-08:00

Mercy Hospital has announced the addition of a new cardiac procedure, becoming the first area medical center to offer Totally Endoscopic Coronary Artery Bypass.

Totally Endoscopic Coronary Artery Bypass surgery, or TECAB, is the latest breakthrough in minimally invasive cardiac surgery, hospitals officials said in a news release.

The Catholic Health Heart Center at Mercy Hospital of Buffalo has announced that it is one of only a handful of centers nationwide offering this revolutionary procedure, which is performed “robotically” through tiny, fingertip-sized portholes, versus a large, 6-10 inch incision with traditional open-heart surgery. John Bell-Thomson, MD, chair of Mercy’s Cardiothoracic Surgery Department, is the only local surgeon and one of the few surgeons in the country performing the TECAB procedure.

Mercy Hospital, located in South Buffalo, is part of the Catholic Health System .

Program Aims to Promote Recovery By Training Personal Guides and Mentors

2012-02-22T10:59:00.000-08:00

The Resource Training Center Set To Offer “Recovery Coach Academy” in Erie County.

Amherst, NY – The Resource Training Center (TRTC) is now offering the CCAR Recovery Coach Academy at its Amherst, NY location at 4255 Harlem Road, according to Monica A. Farrar, MS CRC; CASAC-T, program director at TRTC’s Amherst location.

Recovery Coaching is a form of strengths-based support for those with an addiction to alcohol, drugs or other addictive behaviors, or those in recovery. Unlike licensed counselors and therapists, however, Recovery Coaches cannot assess and/or offer treatment for addiction and/or mental health problems and are not meant to be a substitute for therapy. Recovery Coaches are helpful to clients making decisions about what to do with their life and the part their addiction or recovery plays. In addition, Recovery Coaches help clients find ways to stop addiction (abstinence), or reduce harm associated with addictive behaviors. They can also assist clients in finding resources for harm reduction, detox, treatment, family support and education, local or online support groups or help a client create a change plan to recover on their own.

Recovery Coaches are professionals who have been trained to listen, observe and customize their approach to the individual needs of their clients. They are trained to help clients resolve ambivalence, increase confidence and motivation, and use a strengths-based approach to addiction recovery. For information contact Nancy Cardillo at 833-0408.

Chew and Chat: The Link Between Housing and Health

2012-02-22T10:41:00.001-08:00

On the 4th Tuesday of every month, CHWs and other community members and advocates gather to grab a bite, learn about a specific issue relevant to community health, and share information, resources, and events. This month's Chew and Chat will be held on Tuesday February 28th from 12pm-2pm at the Belle Center (104 Maryland). The featured presenter will be Stephanie Simeon, Executive Director of Heart of the City Neighborhoods, who will discuss the link between housing and health. Lunch will be provided. Please RSVP to chwbuffalo@yahoo.com.ALSO- We are looking to expand the offerings and format of our Chew and Chats. Please attend a meeting to share your ideas, or contact us at chwbuffalo@yahoo.com

Primary Care Physician Joins Buffalo Medical Group

2012-02-22T10:36:00.000-08:00

(Williamsville, NY) – Buffalo Medical Group has added a primary care physician to its large complement of internal medicine and family medicine providers.

Frank J. Voelker, D.O., joined the Buffalo Medical Group, PC, effective February 20. His practice is focused on preventative care and evidence-based treatment.

Following a long career of seeing patients in private practice, Dr. Voelker joins BMG’s Department of Internal Medicine. He will continue to see patients at his present office at 1825 Maple Road, Williamsville, and will relocate to 325 Essjay Road, Williamsville, in the summer of 2012.

A graduate of the University at Buffalo School of Pharmacy and Pharmaceutical Sciences where he received a Bachelor of Science degree in Pharmacy, Dr. Voelker earned his doctor of Osteopathic Medicine at the University of New England College of Osteopathic Medicine. He then completed a residency in Internal Medicine at the UB School of Medicine and Biomedical Sciences and Millard Fillmore Hospitals.

He is board certified by the American Board of Internal Medicine, and a member of both the American College of Physicians and the American Society of Internal Medicine. Dr. Voelker is affiliated with Kaleida Health hospitals.

Roswell Park Cancer Institute Again Included on ‘Great Oncology Programs’ List

2012-02-22T10:32:00.000-08:00

Annual Becker’s Hospital Review feature highlights leaders in research, prevention, treatment and education

BUFFALO, NY — Roswell Park Cancer Institute (RPCI) has once again been included on Becker’s Hospital Review’s annual list of centers that serve as leaders in cancer research, prevention, treatment and education. In selecting facilities for its “Great Oncology Programs” feature, the Becker’s editorial team analyzed data from such sources as U.S. News and World Report, HealthGrades, Thomson Reuters, the National Cancer Institute, the American College of Surgeons and the American Nurses Credentialing Center.

RPCI is one of 70 hospitals and health systems recognized this year for providing full-spectrum care and support services, access to clinical trials, cutting-edge oncology treatment and groundbreaking research.

“Roswell Park was the country’s first cancer center and remains the first and only facility in upstate New York designated as a comprehensive cancer center by the National Cancer Institute,” Becker’s notes in its description of RPCI. “Its patient satisfaction scores are consistently well-above the national average. In the past 10 years, the center has added more than 1,000 new jobs, dedicated an entire hospital facility to Phase I cancer research and formed international strategic partnerships with researchers.”

Becker’s Hospital Review’s 2012 Great Oncology Programs list, including a longer profile of RPCI, can be found at:http://www.beckershospitalreview.com/lists/hospitals-and-health-systems-with-great-oncology-programs.html

RPCI has frequently been recognized for high-quality care and overall excellence. The Institute was again recognized in U.S. News and World Report’s 2011-12 Best Hospitals list for Cancer Care; holds Magnet Recognition Program designation from the American Nurses Credentialing Center; has been named one of the eight best hospitals in the nation for complex or “extremely difficult” cancer cases by AARP The Magazine; and has received other special commendations from BlueCross BlueShield, Optum Health, The Scientist magazine and others.

Becker’s Hospital Review is a bimonthly news publication with approximately 18,500 readers.

Cyber-bullying Law in Erie County

2012-02-17T07:06:00.000-08:00

Cyber-bullying against children and students is on its way to becoming a misdemeanor in Erie County.

The County Legislature unanimously approved a new local law Thursday that would make electronic harassment and bullying against minors and students punishable by a fine of up to $1,000 or up to a year in jail.

Legislator Edward A. Rath III, a Republican from Williamsville, proposed updating the county's laws to specifically address cyberbullying after the death of 14- year-old Jamey Rodemeyer in September. Jamey was a freshman at Williamsville North High School who committed suicide after complaining of being bullied online. The proposal will require approval from County Executive Mark C. Poloncarz to become law. The new proposal would make cyberbullying an unclassified misdemeanor. With that charge, Rath said, most cases against children under 18 would be handled in Family Court and would not result in jail time. Poloncarz will hold a public hearing on the proposal before deciding whether to support it.

Leroy Students and Mass Psychogenic Illness

2012-02-08T10:18:00.000-08:00

A Personal Letter From Dr. Laszlo Mechtler and Dr. Jennifer McVige

Buffalo 08 Feb 2012

At the Dent Neurologic Institute, Drs Jennifer McVige and Laszlo Mechtler have had the privilege to examine and treat 14 of the 19 patients from LeRoy, NY. The diagnosis of Mass Psychogenic Illness (MPI) was not made without considerable input from regional and national experts. We understand the difficulty some of our patients and family members may have with our diagnosis, but it is reassuring to see that most of our patients are improving significantly over the last several

months.

Although we have not evaluated all the patients affected, we have considered many other diagnoses, such as PANDAS and neuro-toxicity due to environmental factors. With the cooperation of the New York State Department of Health and nationally recognized PANDAS specialists, we have ruled out these diagnoses.

We also feel that the media exposure has raised the national awareness of a rare form of conversion disorder, such as MPI, which has not been fully accepted or understood by the public as well as the many in the medical community. At the same time our primary responsibility is to our patients, who unfortunately have not done well with the intense community and media scrutiny.

We do respectfully request that the media remember that we are dealing with impressionable teenagers that have understandable fears and concerns. Although it is not uncommon to have a difference of opinion by treating physicians, I would respectfully request that the patients be treated not through the mainstream media but by credible experts specializing in the field of movement disorder. In this regard, multiple international experts have made themselves available for further consultation. We have strongly encouraged that our patients take advantage of this unique opportunity.

Laszlo L. Mechtler, MD Medical Director, DENT Neurologic Institute

Jennifer McVige, MD, DENT Neurologic Institute Pediatric Neurologist

New Chiropractic Technique Eliminates Muscle and Joint Pain

2012-02-06T12:21:00.000-08:00

Western New York Muscle and Joint Performance Chiropractic just announced its unique approach to chiropractic treatment called Active Release Technique. Many chiropractors do not use this method so many people are unaware of its benefits.

Long hours of sitting or repetitive motions with a keyboard and mouse can lead to scar tissue build up within your muscles. This scar tissue alters normal muscle function that causes pain symptoms such as carpal tunnel, tendinitis, shoulder, neck, back and general joint pain.

Dr. James Phipps, a board certified chiropractor and owner of Western New York Muscle and Joint Performance Chiropractic uses Active Release Technique (ART^®) to break down scar tissue that causes discomfort in people of all ages. From aging baby boomers to teens playing sports with developing muscles, Dr. Phipps has a specific, credentialed ART treatment protocol to relieve these pains.

“I can feel different texture changes in muscles where the scar tissue formed,” said Dr. Phipps. “Using ART’s varying motions I break down this tissue,” said Dr. Phipps. “The technique restores normal muscle and soft tissue function, texture and motion.”

Dr. Phipps develops a personally tailored plan that includes ART, additional muscle therapies and chiropractic adjustments. Many diverse joint and muscle conditions can be successfully treated with this approach. Western New York Muscle and Joint Performance Chiropractic is located at 390 South Youngs Rd. in Williamsville and is open Monday and Friday 8 a.m. to 2 p.m. and Tuesday and Thursday 11 a.m. to 7 p.m. For more information visit www.wnymjpc.com or call 716.629.3100.

Floortime - An Emerging Intervention for Children With Autism

2012-02-05T09:01:00.000-08:00

By Annette Pinder

Growing up in Brooklyn, there was a child on our street who was different. She didn’t talk, and seemed to be off in her own world, as our moms whispered, “She’s autistic.” I found a book at the local library on the topic and secretly yearned to reach this child, but unfortunately never had the opportunity.

So years later, it seemed fitting when my daughter, now 25, made the decision to work with children diagnosed with autism and other communication disorders. It is also a topic no longer discussed in hushed tones, because today one in 110 children in America have an autism spectrum disorder, males are four times more likely to have it, and early intervention is essential.

Applied Behavior Analysis (ABA), is the most common therapy today that has been proven to effectively help children learn skills ranging from making eye contact and following simple instructions, to developing advanced language and social-skills. But new developmental interventions are emerging, as ABA has come under some criticism for producing ‘robot-like’ behavior in children, and for its use of punishment to reduce or eliminate problem behavior.

One program that is gaining attention as an alternative to ABA is Floortime, developed by Dr. Stanley Greenspan. A renowned leader in autism education, Greenspan worked with many young children diagnosed with the disorder. Now older, these children are said to be fully communicative, creative, warm, loving, and joyful. Anecdotal evidence also suggests that parents whose children experienced Floortime found it to be effective.

Floortime meets a child at his or her developmental level, and builds upon their strengths. Child-focused, with the parent or therapist following the child's lead, Floortime incorporates playful positive attention while tuning in to the child's interests. Its premise is that children learn skills from relationships they have with their caregivers and other significant people in their lives. Through interactive child-directed play and experiences children ‘want’ to relate to the outside world.

Recently, when I observed Floortime at Buffalo Hearing & Speech Center (BHSC), a young boy jumped up from the circle of seated children during a lesson enthusiastically pointing to a chart of facial features. Instead of reprimanding the child for speaking out of turn, the instructor immediately seized upon the opportunity to engage the child, thereby increasing his desire to verbalize and interact socially. And it worked!

BHSC offers Floortime to children ages 3 to 7 years, who are eligible, and CEO Joseph Cozzo, is enthusiastic about the results. He explains, “Education is tailored to meet the specific needs of each child and family, and program funding is provided by the NYS Education Department and the County. Classes operate five full days a week combining individual, small, and large group activities. The classroom team consists of staff trained and educated in Floortime. A multidisciplinary team provides services, including speech language pathology, special education, occupational therapy, social work, and music therapy. Physical therapy is included if required on a child's Individualized Educational Plan (IEP).

Cozzo also wants parents to know about BHSC’s outpatient social communication program for children ages 5-18 with Autism Spectrum Disorder, and encourages them to make an appointment to observe the Greenspan/Floortime and the outpatient programs by calling 885-8318. To learn more visit www.stanleygreenspan.com.

WNY Resource:
Buffalo Hearing & Speech Center is headquartered at 50 E. North Street in Buffalo with additional locations in Amherst, West Seneca, Fredonia, and Wheatfield. Visit www.askbhsc.org to learn more.

Eat Well Live Well Challenge

2012-02-02T05:50:00.000-08:00

Employers and Community Organizations are invited to Participate in A Community Wellness Program

The “Eat Well Live Well” Challenge is focused on increasingregular physical activity and nutrition choices that enable individuals toimprove their health while lowering their risk for chronic illnesses. TheChallenge is an affordable wellnessprogram that offers employers andcommunity organizations a valuable opportunity to be proactive in improving health and health care cost management.

Please consider these facts:More than 65 percent of our adult population is overweight, resulting in aone-third increase in the number of diabetes cases. Adult onset diabetesincreases health care costs by 25 percent. Obesity and physical inactivityaccount for 25 to 30 percent of several major cancers. Overweight and inactiveindividuals are at greater risk of cardiovascular disease, including high bloodpressure and stroke.

The World Health Organizationand U.S. Centers for Disease Control concur that 70 percent of chronicillnesses can be prevented with simple lifestyle changes such as eatinghealthier and becoming more physically active. That’s where “Eat Well Live Well”comes in! The “Eat Well Live Well” Challenge is a proven, healthpromotion program that requires a minimal amount of time and investment for a powerfulreturn. The “Eat Well Live Well” participants need only walking shoes,pedometers and the desire to be healthy! The website, www.eatwelllivewell.org, (free foremployers, employees and community organizations) offers user friendlysupport and resources to help participants achieve their wellness goals.

With over 200,000participations to date, the “Eat Well LiveWell” Challenge has received national recognition, (Business Week magazine,11/09) and a Certificate of Recognition for Outstanding Prevention Efforts fromthe U.S. Department of Health and Human Services. The Challenge has beensuccessfully implemented for the past 3 years in the Buffalo/Niagara region,with multiple employers including Rich Products, New Era Cap, the American RedCross, Walsh Insurance Group, M&T Bank and the Buffalo Public School System. A major local employer had this successstory to share:

"The “Eat Well Live Well” Challenge providedus with an excellent opportunity to promote our commitment to a culture ofwellness for our employees (at UB). Employees thought it was challenging yetfun and they felt a lot of camaraderie as a result of the"competition" between teams. We are seeing a lot more walkers oncampus and more produce as snacks as a result. We can't wait to do itagain!" – Kathie Frier, University at Buffalo.

For more information, or to register (required) forthe Information Session or Training Session, please contact the WellnessInstitute at (716) 851-4052 or email beactive@city-buffalo.org.

INFORMATION SESSION Thursday, Feb. 16, 2012, 9:00 A.M. OR 10:30A.M.,

Wegmans, 651 Dick Rd., Depew, NY

TRAINING SESSION Wednesday, Feb. 29, 2012, 12:00 P.M. to 3:30P.M.,

Wegmans 5275 Sheridan Dr., Williamsville, NY

* Returning employers may start between Jan. 15, 2012and May 6, 2012

* New employers may start between Mar. 4, 2012 and May6, 2012, following training

At the Information Sessions,interested employers and community organizations will be invited to attend thefree local train-the-trainer session for employer or organizationrepresentatives. The free trainingwill focus on “how to” successfully implement the “Eat Well Live Well”Challenge. An “Eat Well Live Well”Challenge program/community resources toolkit (cost: $25) will also be providedto those who attend the local ½ day training. A healthful lunch will beprovided.

Please share this invitationwith others you believe might be interested. We look forward to your successfulparticipation in the Spring 2012 WNY “EatWell Live Well” Challenge!

For information contact: Philip Haberstro, BeActive NYS, www.BeActiveNys.org,a statewide health promotion initiative of the non-profit Wellness Institute ofGreater Buffalo. Watch for information on the May 2012 WesternNew York Healthiest Employers Awards. See www.CreatingHealthyCommunities.org for more information.

Why Choose Mini Dental Implants

2012-01-30T07:11:00.000-08:00

by Benjamin D.Oppenheimer, DDS

When David came in to see me he had just been laidoff from work, and the prospect of going on interviews with two missing teethwas overwhelming. When he asked about mini-implants he was shocked to learnthey cost 50% less than regular implants and wanted to know why.

Approximately 50,000,000 people in the U.S. are"edentulous" (lacking teeth) and struggle daily with embarrassmentdue to missing teeth and discomfort due to loose or ill-fitting dentures,disagreeable breath, and the inability to enjoy the foods they love.

While dentalimplants come in a variety of brands and sizes, mini dental implants (MDIs)have becoming increasingly popular due to improved technology and lower cost.An MDI is a miniaturetitanium screw that acts like the root of your tooth, is very thin and small in diameter, and easy to implant even in thinbone. MDIs can also be usedto connect or cement to a crown or bridge, so they are fixed in place insteadof having to be removed like a denture. Sometimes they are used toreplace one or more teeth, or an entire arch of teeth.

TodayMDIs are FDA approved, and able to function as long-term supporting structures,rather than short-term or medium term devices. In fact, somehave been successfully functioning in patients' jaws for several decades. Butit is important to understand that all implant systems, as well as naturalteeth, are subject to potentialfailure due to natural causes, including osteoporosis, poor oral hygiene, wearand tear, poor health, stressful biting habits, and lack of follow-up dentalcare. MDI implants, like regular dental implants, do not carry any actualor implied guarantee as to longevity. However, the loss of a mini dentalimplant is a far less critical event to a patient since it may bereplaced at relatively minimal cost compared to conventional implants, and withminimal associated bone or gum deterioration.

Minidental implants are surprisingly affordable, are usually available at a fractionof the cost of traditional implants, and have been changing the lives ofpatients all over the world. Meanwhile, Dave couldn’t be happier. He says,“Mini dental implants are really affordable, and cost me a fraction of what Iwould have paid for traditional implants. It was painless and I’m reallyhappy!”

Aboutthe Author:
Benjamin D. Oppenheimer, DDS provides both regular and mini dental implants(MDIS). He has lectured to thousands of dentists all over the world, and haswritten extensively on the subject, and placed thousands of dental implants inhis career. He sees patients at his office at 2000 Eggert Road in Amherst. Tolearn more visit www.drmdi.com. To schedulea free consultation and obtain information about a personalized treatment plancall 716-418-7272.

Roswell Park Cancer Institute Announces Vaccine for Cancer

2012-01-24T07:34:00.000-08:00

Dendritic cell vaccine, manufactured in unique RPCI facility, trains body’s defenses to remember, destroy cancer cells

Tuesday, January 24, 2012

The Center for Immunotherapy at Roswell Park Cancer Institute (RPCI) has launched a phase I clinical research study of a dendritic cell vaccine designed to both eradicate cancer cells and prevent disease relapse. Developed at RPCI, the NY-ESO-1 dendritic cell vaccine will be manufactured in the Institute’s new Therapeutic Cell Production Facility using a unique FDA-approved process — making RPCI the first research facility in the U.S. to use a custom-made barrier isolator for vaccine cell production, and the first in the world to use this system in an approved, government-regulated study.

Dendritic cells are the gatekeepers of the human immune system, defending against invaders like bacteria, viruses and cancer. The vaccine to be produced at RPCI will be the first to incorporate a particular form of NY-ESO-1, antiDEC205-NY-ESO-1. “Armed with this specialized protein, the treated cells are then given back to the patient as a vaccine designed to recruit an army of killer immune cells that seek out and destroy cancer,” explains Kunle Odunsi, MD, PhD, Director of RPCI’s Center for Immunotherapy (CFI) and the study’s Principal Investigator.

The new study is also unique in that it’s the first to test a dendritic vaccine given in combination with rapamycin, a compound used to prevent rejection of solid-organ transplant. The study just launched will capitalize on a striking recent scientific discovery by Protul Shrikant, PhD, of the Department of Immunology at RPCI, who found that in low doses, rapamycin confers a previously unknown benefit — it prevents the immune system from using up its cancer-killing T-cells in one quick burst. “We have shown for the first time that rapamycin has the capacity to produce immune cells that have memory attributes,” explains Dr. Odunsi, who is also Chair of RPCI’s Department of Gynecologic Oncology. “The immune cells are trained to live longer and to always remember that cancer cells are bad and should be attacked and killed.”

The ability to stretch out the attack for a long-term, durable response suggests that the vaccine may be effective in preventing disease recurrence. The new NY-ESO-1 dendritic cell vaccine is expected to show great promise in patients with bladder, brain, breast, esophageal, gastrointestinal, hepatocellular, kidney, lung, melanoma, ovarian, prostate, sarcoma and uterine tumors.

The NY-ESO-1 vaccine, tailor-made for each patient, will be produced in RPCI’s Therapeutic Cell Production Facility (TCPF) under the direction of Yeong “Christopher” Choi, PhD, who notes: “We believe that our facility’s custom-made barrier isolator, the unit in which the vaccines are manufactured, is the first of its kind.” The barrier isolator — an Xvivo System processing chamber designed to RPCI’s specifications by BioSpherix, Ltd., Lacona, NY — maintains strict control of the unit’s temperature and atmospheric gases, critical for optimal production of dendritic cell vaccines.

“Those conditions, and the sterile vaccine-manufacturing environment, are rigidly maintained throughout the entire process,” says Dr. Choi. “The Xvivo — which at about 70 square feet is basically a clean room in a box — acts as a physical barrier that protects the cell-therapy product from outside contaminants, resulting in a safer, more predictable manufacturing process.”

The potential of therapeutic vaccines is attracting increasing interest in the field of oncology. Last year, the FDA approved the first therapeutic cancer vaccine, Provenge® (sipuleucel-T), for men with advanced prostate cancer. RPCI’s Center for Immunotherapy is awaiting FDA approval to launch additional cancer vaccine trials, including a vaccine for malignant glioma (a type of brain tumor) and another vaccine for patients with ovarian, fallopian tube, and primary peritoneal cancer.

“This trial will be only the beginning of a very robust program of activity in the area of using the human immune system to fight cancer,” adds Dr. Odunsi. “Our production process holds tremendous potential for applications related to stem-cell therapy and regenerative medicine, and I believe we’re uniquely positioned at RPCI to have the tools, infrastructure and multidisciplinary collaboration to capitalize on these ideas and opportunities both effectively and efficiently.”

The clinical research study will enroll 18-20 eligible patients whose tumors express a specific antigen, known as NY-ESO-1. Apart from the adult male testis, NY-ESO-1 is not expressed in normal tissues of the body, but is expressed in cancers. This may help decrease the risk of side effects from the vaccine, because it should target only the tissues that express NY-ESO-1.

Dr. Odunsi, who developed the NY-ESO-1 vaccine, led previous trials evaluating its effectiveness in treating ovarian cancer. Christine Sable of Lancaster, Pennsylvania, enrolled on one of those studies in February of 2004, after undergoing surgery and chemotherapy for advanced-stage ovarian cancer. Although she faced a 75-80% chance that the cancer would return, her immune system responded strongly to the vaccine, and she has remained cancer-free in the seven years since then, with no side effects.

To learn more about the clinical research studies of the NY-ESO-1 dendritic cell vaccine, call 1-877-ASK-RPCI (1-877-275-7724).

The mission of Roswell Park Cancer Institute (RPCI) is to understand, prevent and cure cancer. RPCI, founded in 1898, was one of the first cancer centers in the country to be named a National Cancer Institute-designated comprehensive cancer center and remains the only facility with this designation in Upstate New York. The Institute is a member of the prestigious National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers; maintains affiliate sites; and is a partner in national and international collaborative programs. For more information, visit RPCI’s website at http://www.roswellpark.org, call 1-877-ASK-RPCI (1-877-275-7724) or email askrpci@roswellpark.org.

More information:

B-roll video (QuickTime H.264 1920x1080, 329 MB) available for download at:https://files.me.com/rpcicreative/wn2kxt.mov

About this clinical trial: http://www.roswellpark.org/clinical-trials/list/191511

Hiding in Plain Sight: Incognito Braces!

2012-01-16T11:23:00.000-08:00

How important is your smile? Rochester-based firm Harris Interactive polled 1,000 people ages 18-54 to explore the importance of a good smile in business, relationships, and self-esteem. The results may surprise you:

• 85% think a good smile is important in attracting a new partner

• 75% think it’s important for getting a new job

• 90% were “very likely” to notice a smile in a first meeting

• 71% said a nice smile makes it easier to make friends

• 86% think people with good teeth are more attractive

• 33% said they would not kiss someone with bad teeth

Today, a good smile is easier to come by. For those who need braces, the days of clunky metal brackets, or “train tracks,” may be numbered. Although traditional braces are still commonly used, more people are choosing to have their teeth straightened with innovative new technologies.

One of the newest trends in orthodontics has been the development of invisible braces. There are two main types. One is on the front of the teeth, while the other newer technology utilizes “lingual” behind-the-teeth braces. Lingual braces are extremely popular with teens and adults who want the benefits of orthodontics without anyone knowing they are being treated. They also provide an option for those who wish to have hidden braces for career purposes, such as actors, TV broadcasters, and celebrities. But anyone can benefit, since appearance may be important to success and career development in many fields. This may be why 1 in 5 people wearing braces today are adults!

Cosmetic concerns aren’t the only reason that people need braces. One local orthodontist Dr. Kathryn Rand says she sees many adult and adolescent patients who have a malocclusion, or bad bite. She says teeth that don’t align correctly often wear down quickly, resulting in abnormal tooth surfaces, difficulty chewing, and damage to supporting bone and gum tissue, all of which may result in the need to have teeth crowned in later years. Fortunately, healthy teeth can be moved at any age, so lingual braces can help prevent future expensive dental treatments while still allowing for a normal lifestyle.

In addition to offering traditional treatment options, Dr. Rand is the only orthodontist in the area to offer “Incognito” lingual braces. She also travels frequently, educating other orthodontists in the use of Incognito braces. She states that patients who choose lingual braces benefit from completely customized braces that are unique to their individual situation. Patients report optimal comfort while undergoing treatment and they love having the braces hidden behind their teeth.

If you have concerns about your teeth, talk to your family dentist. Orthodontic treatment is a viable option for almost anyone, young or old, and can fit in with your current lifestyle – you can sing, play a musical instrument, dine out, kiss, and even have your picture taken! And for many patients, braces can be hidden from plain sight by choosing behind-the-teeth braces.

Dr. Kathryn Rand is a professor of orthodontics at UB. She maintains an orthodontic practice, and is the exclusive provider of 3M Incognito Braces in the Buffalo Niagara region. For more information visit www.hiddenbraces.com. To arrange for a free consultation with Dr. Rand call 675-0155.

Erie County Department of Senior Services Tools for Caregivers Classes

2012-01-12T14:51:00.000-08:00

Register Now for Powerful Tools for Caregiver Classes
in Amherst, Buffalo, Hamburg, Kenmore

A six-week educational program designed to provide caregivers the tools needed for taking care of themselves is now being offered. Through six 2 1/2 hour sessions held on a weekly basis, caregivers learn to reduce stress, improve self-confidence, better communicate feelings, and locate helpful resources. Attendees also learn how to increase their ability to make tough decisions and balance their lives. Pre-Registration is required - Call 858-2177or e-mail caregiver@erie.gov for more information about Powerful Tools for Caregivers Classes and to register. There is a $25 cost for the course, which includes a copy of The Caregiver Helpbook*

*Complete course cost is covered for all Blue Cross/Blue Shield of WNY and Independent Health members.

** Course cost at this location is covered in full by CHF Cultural Diversity Grant funding for those that are uninsured.

Additional classes are being scheduled. For more information or to register, contact: Erie County Department of Senior Services at 858-2177 or e-mail: caregiver@erie.gov Class listing is also on our website at:erie.gov/depts/seniorservices.

Schofield Residence 3333 Elmwood Ave., Kenmore	Thurs.	March 1 – April 5, 2012 10 am – 12:30 pm
VA WNY Healthcare System Northtown Business Center 3131 Sheridan Dr., Amherst FREE Respite care for the memory impaired is offered at this class – inquire at registration	Tues.	March 8 – April 12, 2012 6:00 -8:30 pm
Amherst Senior Center 370 John James Audubon Pkwy., Amherst FREE Respite care for the memory impaired is offered at this class – inquire at registration	Mon.	March 19 – April 23, 2012 12:30 pm – 3 pm
Hispanics United of Buffalo** 254 Virginia St., Buffalo 14201 (This class will be conducted in Spanish)	Wed.	March 21 – April 25, 2012 4:00 – 6:30 pm
ElderWood Village at Rosewood 76 Buffalo St., Hamburg 14075	Tues.	May 15 – June 19, 2012 6:00 pm – 8:30 pm

WNY Genome Project and What It Means to You

2012-01-11T10:58:00.000-08:00

Imagine being able to examine your genetic makeup to determine if you are likely to develop a disease. Imagine being able to receive treatment and medication designed specifically for you in the most effective dose.

One of the most important aspects of modern medicine is genetics, or the science of genes and heredity and what makes us different from one another. The genetic makeup (genome) for one individual is the entirety of that person’s hereditary information. Now imagine the ability to compile and analyze the genome of an entire community to examine the predispositions of its members to common diseases like cancer, diabetes, heart disease, multiple sclerosis, lupus or hypertension (high blood pressure).

In December Roswell Park Cancer Institute (RPCI) was granted $5.1 million by Governor Cuomo to lead a project that will do just that, and Donald L. Trump, MD, RPCI President and CEO, is thrilled. He predicts, “The RPCI Genome Project will significantly enhance our ability to develop personalized, more effective medical care plans and treatments for citizens of Western New York and beyond, but it is just a beginning.”

Dr. Trump explains, “The project will begin with cancer, where we already have experience and infrastructure, including a large database of individuals. One goal is to individualize and personalize treatments. For example, anticoagulant drugs may be dosed differently based on how each individual metabolizes the drug. Another is tamoxifen, a well-documented drug for breast cancer prevention. We need to determine which patients are most likely to benefit from specific drugs and determine appropriate individualized dosages to minimize side effects. Ultimately, the goal is to expand our capability well past cancer and develop effective and customized treatments for all individuals.”

With this pilot funding, 1,000 area residents will be asked to donate a blood sample and provide detailed medical information. Patients’ privacy will be fully protected and their data will not be shared with insurance companies or serve as a basis for denying coverage based on their predisposition to a disease. In fact, only the health care provider and the individual themselves will have access to the information.

So what else is so exciting about the project? Dr. Trump says, “It will mean many jobs for Western New Yorkers, significantly boosting our economy.” Meanwhile, recruitment for a Project leader is underway, and people with cancer expertise, data collection and analysis will also be needed. Dr. Trump adds, “We also know that it will attract more money to our region, as happened with the genome project in Tampa, Florida at the H. Lee Moffitt Cancer Center, where the Merck Pharmaceutical company invested $100 million in a similar endeavor.”

So why was Western New York selected? Dr. Trump says it’s because of our region’s cutting-edge science and technology, broad partnerships with many constituents, and the potential for job growth and economically rewarding partnerships.

Dr. Trump and Deputy Director Candace Johnson, PhD, will lead the RPCI Genome Project as Co-Principal Investigators. Partners include the University at Buffalo, Kaleida Health, the Catholic Health System, Erie County Medical Center, HealthNow/BlueCross BlueShield, Independent Health, Univera Healthcare, The P2 Collaborative and HEALTHeLINK. For more information visit roswellpark.org, call 1-877-ASK-RPCI or send an email inquiry to askrpci@roswellpark.org.

Managing Chronic Health Conditions Wirelessly in Buffalo

2012-01-11T10:55:00.000-08:00

Regardless of age, sex, ethnicity, race, education or location, the number of Americans who are obese, diabetic or suffer from heart and other chronic diseases continues to rise. Now new wireless mobile technology has the potential to improve patient health and wellbeing. And best of all – the patient doesn’t even need to operate or understand the technology, and it’s available right here in Buffalo!

So how does it work? Brian Egan, CEO of Advantage Home Telehealth (ADHT), explains that a telehealth kit, which includes a smartphone, telehealth software, and devices to monitor vital signs like blood pressure, weight, blood oxygen, and glucose are brought to a patient’s home. The smartphone sits discreetly in a cradle, while the individual can take their vital signs from anywhere in their home. Readings are immediately sent wirelessly from the vital sign device into the smartphone to the patient’s health record. If irregularities are detected, the clinical monitoring center is alerted and a call is made to the patient. Symptoms, including diet and exercise changes are reviewed.

Patients can also be reminded to check their vital signs. The telehealth kit can be used anywhere – at work school or while on vacation. And for those who have trouble managing multiple medications, a teleview medication unit is available that allows pills to be viewed remotely while in the tray. The patient is reminded to take the medication, and alerts are sent to the monitoring center if a pill is missed.

W. Cline, a local ADHT patient, said, “Of the many positive experiences that I had since having my vital signs monitored by ADHT was after a dialysis treatment. My blood pressure was low, and within minutes an RN from the ADHT clinical call center contacted me to ask how I was feeling. He asked me to take my blood pressure again. I felt cared for, and reassured knowing that someone was monitoring my vital signs, and providing me with helpful coaching.”

Egan is very excited about the technology and says, “Remote monitoring is particularly beneficial for people with chronic illnesses, who want to remain at home. It is helpful to those who live in rural and remote areas and decreased access to healthcare facilities.” Even more important is the peace of mind remote monitoring offers to the overwhelming number of people who are sandwiched in between balancing a busy work life, while caring for their immediate and extended families.

It is estimated that there are 69 million caretakers in the United States. Now, thanks to the proliferation of mobile products and services, ease-of-use and continued innovation by the wireless industry, the use of remote home monitoring has the potential to revolutionize our healthcare system. Even more significant is that Western New Yorkers can access this technology to improve their lives and the lives of their loved ones right now.

ADHT provides comprehensive technology and services for individuals, insurance companies, physician groups, hospitals, clinics, visiting nurse associations and other health care providers serving patients with health conditions and medication management requirements locally and nationally. A monthly fee is charged based upon the vital sign devices and medication monitoring devices needed. For a free trial see www.givehomehealth.com.

WNY Resource:

Advantage Home Telehealth, Inc.
The Innovation Center at the Buffalo Niagara Medical Campus

640 Ellicott Street, Suite 400

Buffalo, New York 14203

www.advtelehealth.com
www.givehomehealth.com

(716) 218-7169

Support Available for Those Looking to Start New Year Tobacco-Free

2012-01-03T11:34:00.000-08:00

BUFFALO, NY — There are close to 3 million smokers in New York State, and about three-quarters of them say they want to quit. A new advertising campaign will remind New Yorkers about the risks of smoking and the free, 24/7 services that can help them keep a resolution to quit tobacco for good.

The campaign consists of two television commercials that will air throughout January. The ads, Doesn’t Kill and Emphysema, show the physical damage cigarettes can cause to people who smoke. Local New Voice Club members who have had their voice box removed as a result of smoking are living examples of the impacts highlighted in the ads. “It’s very depressing to live like this,” says Joe Corbi, one of three New Voice Club members featured in companion videos. “It’s changed my life financially and emotionally, and has affected my family.”

The ads also direct smokers to the services available through the New York State Smokers’ Quitline (1-866-NY-QUITS). The Quitline, based at Roswell Park Cancer Institute (RPCI), provides free quit coaching and nicotine patches to New York residents who want to stop smoking or using tobacco. The spots, along with companion videos featuring interviews with New Voice Club members who offer smokers quit advice and encouragement and share their experience of losing their ability to speak as a result of past tobacco use, can be viewed at the Quitline website: http://www.nysmokefree.com/Subpage.aspx?P=50&P1=5030.

“So many tobacco users are ready to quit and finally overcome their nicotine addiction at this time of year; support from friends family and the Smokers’ Quitline can make the difference in helping them quit for good,” says Andrew Hyland, PhD, Chair of RPCI’s Department of Health Behavior and Director of the New York State Smokers’ Quitline.

Services available through the Quitline include a free nicotine patch starter kit, quit coaching, self-help materials, motivational messages and daily tips. The Quitline can be reached at 1-866-NY-QUITS (1-866-697-8487) Monday through Thursday, 9 a.m. until 9 p.m., and Friday through Sunday, 9 a.m. until 5 p.m. (taped messages of support available in off-hours). An online smoke-free community is available 24/7 athttp://www.nysmokefree.org, and additional tips and resources can be found at http://www.facebook.com/NYQuits andhttps://twitter.com/nysmokefree.

Editor’s note: Experts from Roswell Park Cancer Institute and members of the New Voice Club of the Niagara Frontier are available to discuss cessation and the effects of tobacco use. Contact Annie Deck-Miller at 716-845-8593 or annie.deck-miller@roswellpark.org to schedule an interview.

RPCI EARNS LEAPFROG TOP HOSPITAL RECOGNITION, ASCO QUALITY CERTIFICATION

2011-12-19T14:51:00.000-08:00

Two prestigious quality designations are latest commendations of RPCI from national organizations

BUFFALO, NY — Roswell Park Cancer Institute (RPCI) has again been recognized at the national level for providing high-quality, patient-centered care. One of only three National Cancer Institute-designated comprehensive cancer centers in New York State, RPCI this month received Leapfrog Top Hospital recognition for the second consecutive year and earned Quality Oncology Practice Initiative (QOPI) Certification from the American Society of Clinical Oncology (ASCO).

The Leapfrog Top Hospital designation puts RPCI in a class representing just 5% of eligible hospitals — 65 from a field of nearly 1,200. The Leapfrog Group, a coalition of public and private employers, selects hospitals for the designation based on an annual national survey measuring performance in areas such as error prevention and nurse and physician staffing — the most complete picture available of a hospital’s record on quality and patient safety.

“For the second year in a row, Roswell Park Cancer Institute has achieved the highest distinction for quality and patient safety that any hospital in America can achieve. We are proud to count them among the select group of 2011 Leapfrog Top Hospitals,” said Leah Binder, CEO of The Leapfrog Group. “As the demand for information about hospital quality grows, hospitals like Roswell Park that participate in Leapfrog’s annual hospital survey are providing a great service to their community by making important information readily available.”

Launched by ASCO in 2006, the QOPI enables medical facilities to examine the quality of care they provide to patients based on evidence-based guidelines and established quality measures. Its rigorous set of more than 100 quality measures was developed by practicing oncologists and quality experts, and spans the continuum of cancer care. The QOPI Certification Program was launched in 2010. RPCI is one of approximately 100 facilities nationally to earn the certification, and one of only seven in New York State.

“Consistency is one of the most important aspects of high-quality delivery of care,” said Donald L. Trump, MD, FACP, RPCI President and CEO. “To be recognized by national organizations as respected as the Leapfrog Group and ASCO, we have to not only be able to provide great and safe care but to have a proven track record of doing so routinely.”

RPCI has frequently been recognized for high-quality care and overall excellence. The Institute was again recognized in U.S. News & World Report’s 2011-12 Best Hospitals list for Cancer Care; holds Magnet Recognition Program designation from the American Nurses Credentialing Center; has been named one of the eight best hospitals in the nation for complex or “extremely difficult” cancer cases by AARP The Magazine; and has received other special commendations from BlueCross BlueShield, Optum Health, The Scientist magazine and others.

About The Leapfrog Group, ASCO and RPCI:

The Leapfrog Group is a coalition of public and private purchasers of employee health coverage founded a decade ago to work for improvements in health care safety, quality and affordability. The annual survey is the only voluntary effort of its kind. More information is available at http://www.leapfroggroup.org.

The American Society of Clinical Oncology (ASCO) has more than 30,000 members and is the world’s leading professional organization representing physicians who care for people with cancer. For more information, go tohttp://www.asco.org.

For more information, visit RPCI’s website at http://www.roswellpark.org, call 1-877-ASK-RPCI (1-877-275-7724) or email askrpci@roswellpark.org.

A Hanukah Favorite - Latkes!

2011-12-11T06:34:00.000-08:00

Fried food is traditionally eaten on Hanukkah in commemoration of the oil that miraculously burned for eight days when the Maccabees purified and rededicated the holy Temple in Jerusalem. Fried Potato Pancakes (called Latkes in Yiddish) are the hands-down, mouth-open holiday favorite. Here’s a healthier version made from sweet potatoes.

Sweet Potato Latkes (cholesterol-free)
from the kitchen of Laura Strauss

6 medium sweet potatoes

6 ounces egg substitute

4 scallions (diced)

2 tbsp. honey

1/4 tsp. cinnamon

1/4 tsp white pepper

1 1/2 tsp salt

4 tbsp. flour

1 tsp. minced garlic

1/2 tsp. baking powder

Oil for frying (canola oil recommended)

Makes about 20 latkes

Shred potatoes in food processor ( It is not necessary to peel the potatoes.)

In a large bowl combine potatoes, egg substitute, scallions, honey, cinnamon, pepper, salt, flour, and garlic.

Work mixture with your hands until thickened.

Form into 2-3 ounce patties and press thin.

In a large frying pan, heat 1/4 inch of oil until hot.

Fry patties until golden brown on both sides.

Drain on paper towels.

Serve hot.

Wanted: Physician Assistants - A Growing Career

2011-12-11T06:13:00.000-08:00

Wanted: Physician Assistants - A Growing Need for Passionate, Caring Professionals

When Virginia Kaufman graduates in May she will be a Physician Assistant (PA), and she can’t wait. Virginia didn’t always know that she wanted to become a PA, and wants to tell others who share her passion for pursuing a career in the medical profession about this unique opportunity.

PAs are healthcare professionals authorized to practice medicine as part of a team with physicians. There are 81,000 certified PAs licensed to practice in all states, the District of Columbia, the Commonwealth of the Northern Mariana Islands, Guam and the U.S. Virgin Islands. They deliver a broad range of medical and surgical services, and are trained to:

• Conduct physical exams

• Obtain medical histories

• Diagnose and treat illnesses

• Order and interpret tests

• Counsel on preventive health care

• Assist in surgery

• Prescribe medications

It takes a team of skilled professionals to deliver quality health care, and PAs are increasingly becoming vital members of the healthcare team. Interestingly, the role of the PA began in the 1960s to fill a need created by a shortage of physicians. In fact, the first PAs were military medics with experience in critical care and emergency medicine during active duty. Now with the demand for health care services outpacing the number of physicians available, PAs are again helping fill the void.

PAs can practice medicine in any specialty from family medicine to surgery to cardiology. A PA also gains clinical privileges in a hospital setting much the same way as a physician would. PAs are often the primary health care provider for individuals and families, and physicians who have a PA on their team know that they are qualified to perform up to 80 percent of primary and preventive care.

To become licensed to practice, PAs must attend an accredited program and pass an exam administered by the National Commission on Certification of PAs. They must obtain authorization to practice through state licensure, registration or certification, and complete 100 hours of continuing medical education every two years, and pass a recertification exam every six years. Most students have a BA/BS degree and prior healthcare experience before admission to a PA program, and 80 percent of PA programs award a master’s degree. Today, approximately 12,470 students are currently enrolled in PA programs, and more than 6,000 PA students graduate each year. They earn a median annual salary of $90,000, and the U.S. Bureau of Labor Statistics (BLS) projects that the number of PA jobs will increase by 27 percent between 2006 and 2016.

Clearly, becoming a PA holds promise for a great future. Now a new book is available to anyone contemplating a career as a PA that provides helpful information and resources, including a list of schools, websites, salary information and more. But Hratch Karamanoukian cautions, “Although becoming a PA offers significant earning potential, it isn’t just about the money. It’s about having passion for what you do.” Listen to what one PA has to say at http://youtu.be/NnFKdEZIVTU.

WNY Resource:
The Past, Present and Future of Physician Assistants in America, by Hratch Karamanoukian, M.D., Raffy Karmamanoukian, M.D., and Virginia Kaufman, PA-S, copyright November 2011. For a look inside, or to purchase a copy visit www.Amazon.com.

When Is a Headache More Than Just a Headache?

2011-12-11T06:02:00.000-08:00

What would cause a 34-year-old woman to waken with severe and throbbing head pain, nausea and dizziness? A 9-year-old to have a headache lasting four months? Or an otherwise healthy 32-year-old woman to have severe headaches and seizures?

These are just some of the difficult cases of severe headache pain the DENT Neurological Institute sees every day.

Laszlo Mechtler, M.D., Director of DENT’s Headache Center and President elect of the American Society of Neuroimaging, says, “Most of the people we see have primary headache disorders, such as migraine and tension type headaches. A common medical complaint, they are experienced by 75% of the population with over 5% seeking medical aid. In fact, about 16% of emergency room (ER) visits are attributable to headache complaints.”

Mechtler explains, “Patients who are the most complex are those where headaches come from a secondary cause, which includes more than 316 life-threatening disorders and illnesses. They are the toughest cases, and neuroimaging studies are required to determine the underlying cause.” Some of the key symptoms or red flags that help clinicians determine if further studies are needed include:

· First or worst headache, onset of headaches after age 50, following head trauma, or in someone with cancer or HIV

· Chronic daily headaches unresponsive to treatment or headaches with increased frequency and severity

· Headaches always on the same side, or following exertion, strain or positional changes

· Headaches accompanied by fever, stiff neck, rash, atypical aura, abnormal neurological exam or seizures

Of adults with headache seen in the ER, only 16-20% have secondary headaches, as compared with 77% of children. Of these children 45% suffer from secondary headaches due to neurological causes. Red flags in children differ from adult warning signs and include:

· Persistent headaches that last less than 6 months but don’t respond to treatment

· Headaches that awaken the child from sleep or occur when awakening or with episodes of confusion or disorientation

· Family and/or medical history of central nervous system involvement or abnormal neurological test results

DENT is home to the only Headache Center in Western New York where more than 17,000 patients are seen yearly. In fact, the only other centers within reasonable traveling distance are located in Cleveland, New York City and Philadelphia. Trained staff at the Center include physicians who are board certified in neurology, neuroimaging, and neuro-oncology supported by physician assistants, nurse practitioners, psychiatrists, nurses and clinical research staff. Research and education are ongoing, as are new treatments and medications unavailable anywhere else. An onsite infusion lab and Urgent Care Center assures that patients can be seen 24/7. Meanwhile, Dr. Mechtler says, “About 120,000 people in our region suffer from migraines, but only 15% receive treatment. To learn more about headaches visit www.headache-advisor.com.

WNY Resource:

DENT Headache Center
716-250-2000
www.dentinstitute.com

ROSWELL PARK WILL LEAD $5.1M GENE-SEQUENCING EFFORT FUNDED BY NYS INITIATIVE

2011-12-10T16:03:00.000-08:00

Effort will examine genetic factors in common diseases and advance field of personalized medicine

BUFFALO, NY — The Roswell Park Cancer Institute Genome Project was approved December 8, 2011 as part of Gov. Andrew Cuomo’s Regional Economic Development Council initiative. RPCI will lead this project, which will compile and analyze the detailed genetic data (the “genomes”) of Western New York citizens. This will significantly enhance our ability to develop personalized, more effective medical care plans and treatments for citizens of Western New York (WNY) — and beyond.

The $5.1 million award for the RPCI Genome Project covers the two-year pilot phase of the project. During this phase of the project, 1,000 area residents will be asked to donate a blood sample and provide detailed medical information; all these data will be collected in a fully protected way to ensure the privacy of all participants. The Genome Project will examine genetic factors that play a role in cancer as well as common diseases such as diabetes, heart disease and hypertension.

RPCI President and CEO Donald L. Trump, MD, FACP, and Deputy Director Candace Johnson, PhD, will lead the RPCI Genome Project as Co-Principal Investigators. Partners include the University at Buffalo, Kaleida Health, the Catholic Health System and Erie County Medical Center as well as the three major health insurers in WNY (HealthNow/BlueCross BlueShield, Independent Health and Univera Healthcare), The P2 Collaborative and HEALTHeLINK.

The Roswell Park Cancer Institute Genome Project was championed by WNY Regional Economic Development Council (WNYREDC) Co-Chairs Satish K. Tripathi, University at Buffalo President, and Howard A. Zemsky, Managing Partner of Larkin Development Group, along with Andrew Rudnick, President of the Buffalo Niagara Partnership and Health & Life Sciences Co-Chair for the WNYREDC.

“Together, they ably and energetically oversaw the maturation and development of this proposal, working closely with RPCI at every stage,” said Dr. Trump. “We are grateful for the leadership they, Governor Cuomo and all the members of the Western New York Regional Council have provided through this ambitious development program, and eagerly look forward to implementing this effort.”

For more information, visit RPCI’s website athttp://www.roswellpark.org, call 1-877-ASK-RPCI (1-877-275-7724) or email askrpci@roswellpark.org.

Community Leaders Find Solution for Kidney Transplant Patients

2011-12-06T15:53:00.000-08:00

Fresh off the heals of the National Kidney Foundation closing the doors to the Buffalo, NY office, community leaders have come together to find a solution for local kidney and transplant patients. The Northeast Kidney Foundation would be working with local clinicians, patient advocates and transplant professionals to reinstate services no longer available in the community.

Barbara Breckenridge, a kidney transplant recipient, long time patient advocate and former staff of the NKF, is thrilled that a solution is available. “I know the needs of the patients,” Breckenridge said. There are so many issues these patients are dealing with, when these services were taken out of the community it was a great loss.”

The Northeast Kidney Foundation, based in Albany, is a former affiliate of the NKF, separating in July. In the newly created partnership with the Buffalo region, the Foundation will reinstate patient services, continue community screening programs, patient education, community outreach and education, school based programs, and all the services the community has received through the years. “We are most thrilled that we can say there are no more gaps in service,” said Carol LaFleur, executive director of the Northeast Kidney Foundation. “At the end of the day, what is most important is that patients have the resources that they need, and that the Buffalo region knows the great dedication of their community leaders to serving the patients and family members affected by kidney disease.”

Services have already begun to be reinstated, including patient emergency grants and transportation subsidies, and just a few weeks ago a kidney screening was held where more than 40 people came out to learn if they were at risk for kidney disease or exhibiting early signs of the disease. Dr. Brian Murray, a nephrologist and medical director for Erie CountyMedical Center, volunteered at the screening. “Offering programs like this in the community is so important for those at risk. What a great experience to be able to talk with people and educate them about a disease that many are unaware that they may have.” Also volunteering at the kidney screening were Dr. Jennie Hom, a nephrologist at Erie County MedicalCenter, and staff of Upstate New York Transplant Services, who manned the lab station. “My staff enjoyed it – it gave them an opportunity to get out in the community and put their phlebotomy skills to work and provide a great service to those at risk for kidney disease. Collaboration has always been the best way to meet the needs of our community, and UNYTS is a proud partner to many and is looking forward to this collaboration,” said Mark Simon, CEO of UNYTS.

While the Northeast Kidney Foundation moves forward with service implementation, community leaders are also keeping an eye on the possibility of creating a locally based organization. Discussions will continue over the next several months but for now the message is clear – the needs of patients, family members, and clinical professionals will be met through the collaboration with the Northeast Kidney Foundation.

There are several important dates that the community should be aware of. They include:

January 22, post holiday party for patients and family members

March 3, 2012 – free kidney screening for those at risk of kidney disease, 10 am – 2 pm

March 8, 2012 – World Kidney Day and Gift of Life Celebration, 5 pm

March 9, 2012 – Walk for Kidneys Kickoff Breakfast

June 3, 2012 - Walk for Kidneys

For more information on these activities, please contact Barbara Breckenridge at 716-885-7215 or Carol LaFleur at 518-533-7880 and visit www.healthykidneys.org.